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These results underscore the challenge of treating MASH

Retatrutide is an investigational peptide being evaluated in clinical research for its effects on metabolic pathways related to weight regulation

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[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Wu Q.J., Yang G., Zheng W., Li H.L., Gao J., Wang J., Gao Y.T., Shu X.O., Xiang Y.B

Metabolic considerations : While adipose tissue has some metabolic activity, skeletal muscle is the primary contributor to resting metabolic rate and heat production