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The -amino group of Lys 185 acts as a general base, abstracting a proton from the hydroxyl group at C-3 of 6-phosphogluconate

Cancer Cell 19 , 416428 (2011)

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GSH is essential for immunomodulation of both innate and adaptive immune system functions, including T-lymphocyte proliferation, polymorphonuclear neutrophil phagocytosis, and dendritic cell functions, and is also important for fine-tuning the innate immune response to infection and for the first step of adaptive immunity involving antigen-presenting cell (macrophages, dendritic cells)-related antigen presentation (Morris et al., 2013