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The date at the first prescription fill (claim) of any dose less than 2.4 mg of the drug (0.25, 0.5, 1.0, or 1.7 mg) was designated as the index date

Taken together, UNC10415667 reveals that slightly larger benzaldehyde-based degraders can effectively recruit FBXO22 via C326 to promote the potent degradation of NSD2 without requiring chemical protection or bioactivation

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10.1016/j.exer.2014.05.004