Despite decades of pharmacological research and a massive and increasing prescription of antidepressants, less than half of the treated subjects (48%) showed improvement (symptom remission) after 6 months of treatment, a percentage that drops to 34% if functional remission is assessed [7]
Ostadmohammadi V, Soleimani A, Bahmani F et al (2020) The effects of melatonin supplementation on parameters of mental health, glycemic control, markers of cardiometabolic risk, and oxidative stress in diabetic Hemodialysis patients: A randomized, Double-Blind, Placebo-Controlled trial
By contrast, among adults with diagnosed diabetes: About 26% to 27% use injectable GLP-1 medications
found that DHA triggered ferroptosis to eliminate the activation of HSC, which characterized by iron overload, GSH depletion, lipid ROS accumulation, and peroxidation, whereas Fer-1 and Lip-1 inhibited the DHA effect (93)
As more individuals grapple with obesity and its associated health risks, this medication offers a beacon of hope, appealing to both healthcare providers and patients alike
