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Prog Neuropsychopharmacol Biol 19 : 117133 Forster EA, Cliffe IA, Bill DJ, Dover GM, Jones D, Reilly J, Fletcher A

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Conformational changes of these conserved residues especially the transmission switch residues F272 6.44 and W276 6.48 have been suggested to link the extracellular agonist-binding to the cytoplasmic receptor activation and G protein-coupling for class A GPCRs (Supplementary Fig

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10.18632/oncotarget.27650 Oncotarget 85 MarthaP

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In other words, the premise is that only when the fat cells are "moving" can L-carnitine be used as a "transporter"

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