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The standard Phase 2 trial schedule began at 0.5 to 1mg weekly, escalating every 4 weeks through 2mg, 4mg, 8mg, and up to 12mg

Women using tirzepatide with oral contraceptives should use non-oral contraception or add a barrier method for 4 weeks after initiation and after each dose increase

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This finding is also consistent with that reported with liraglutide [36]