The protein was purified through heparin affinity chromatography using 50 mM sodium citrate buffer, pH 6.0, then processed using ion-exchange chromatography (IEC), and finally purified by SEC on a Superdex 75 column (HiLoad 16/600, Cytiva)
Int J Pharm 125439 Wharton S, Blevins T, Connery L, Rosenstock J, Raha S, Liu R, Ma X, Mather KJ, Haupt A, Robins D, Pratt E, Kazda C, Konig M (2023) Daily oral glp-1 receptor agonist orforglipron for adults with obesity
Keep electrolyte beverages on hand during titration weeks as a preventive measure
You will also want to avoid forgetting about other cost factors such as specific dosage, doctor visits and consultations
Patients should maintain a medication log documenting the appearance of each vial or dose, including color intensity, clarity, and any observed changes