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At this level, some individuals may experience mild digestive friction

Individuals with severe gastroparesis or significant gastrointestinal disease may be at greater risk of exacerbated symptoms and would need careful individual assessment before commencing treatment

But the side effects that receive the least attention online are the ones that matter most to anyone considering it: significant lean muscle loss documented by DEXA scanning, dopamine suppression that can flatten mood and drive, and dosing decisions where the difference between 8 mg and 12 mg is roughly 1 percent more fat loss and approximately double the side effects

It means we are relying heavily on animal data and anecdotal human reports

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