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This is not due to thyroid damage, but rather because: Weight loss alters hormone needs Improved metabolic health can change dosing requirements My Clinical guidance to patients: If you lose 1020 pounds, recheck thyroid labs within 812 weeks to avoid over- or under-treatment
When to Discard and Safety Considerations Discard GLP-1 medication if it has been frozen, left unrefrigerated for more than 48 hours, appears cloudy or discolored, or has passed its expiration date
Conclusion Clinical trial data from large, controlled studies demonstrate the efficacy and safety of GLP-1 agonists in terms of A1C reduction, beneficial effects on body weight, and a low risk for hypoglycemic events when used as monotherapy
The majority of adults were prescribed their first GLP-1 receptor agonist in 2017 or 2018
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