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See WO 2009/047728, supra, incorporated herein by reference

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Almandoz JP, Wadden TA, Tewksbury C, et al

Cell Metabolism Obesity Reviews Frontiers in Endocrinology Nature Reviews Endocrinology The Lancet Diabetes and Endocrinology JAMA Cardiology Frontiers in Endocrinology Circulation 2022 Scientific Statements from the American Heart Association Diabetes, Obesity and Metabolism Joint consensus statement published in Diabetes Care