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Potential CNS Access : Some research suggests nasal administration may facilitate direct transport to the central nervous system via olfactory and trigeminal nerve pathways, though this remains an area of ongoing investigation [5]

Athletic or performance enhancement

A few commenters recommended that CMS consider matching addresses listed in the Shipping Addresses section of the 340B OPAIS database as additional locations that could be dispensing 340B-eligible claims on behalf of a covered entity in order to more accurately identify in-house pharmacies or pharmacies dispensing 340B-eligible drug on behalf of a covered entity but not registered as contract pharmacies in the 340B OPAIS database

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