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No other potential conflict of interest relevant to this article was reported

Symptoms of Semaglutide-Related Anxiety Anxiety triggered by semaglutide typically manifests as restlessness, racing thoughts, mild panic sensations, or heightened startle response rather than sustained clinical anxiety

Semaglutide can be a long-term solution for weight loss , provided it is accompanied by a healthy lifestyle and dietary changes

Yang C-Y et al (2021) Synbiotics alleviate the gut indole load and dysbiosis in chronic kidney disease. Cells 10(1):114

This study in humans shows that altered gut microbiota mediates some of metformins antidiabetic effects in treatment-naive patients with type 2 diabetes mellitus