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For the first time, science is delivering a pill that can achieve weight loss once thought possible only with surgery or injections

There is no evidence that combining these medications increases the risk of serious adverse events such as serotonin syndrome (a rare but serious condition associated with excessive serotonergic activity)

Many patients experience serious side effects, including gallbladder complications

The decision to use GLP-1 receptor agonists should be made on an individual basis, weighing the potential benefits against the risks for each patient

The story gets one step weirder: While Handler stopped taking the medication when she realized it was not right for me, she gave her leftover doses to friends, which is certainly not medically advised