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In recreational athletes, supraphysiological GH doses are often used either alone or in combination with other doping substances (140), and studies have shown that GH improves anaerobic sprint capacity, but not strength and endurance (141), and increases GH, IGF-I and fasting insulin levels (142, 143) mimicking those seen in acromegaly patients ( Table 1 )

Bariatric procedures or surgery were go-to options for many people prior to GLP-1 medications

I havent seen that, personally, he says

This approach provides steady-state tissue levels without the peaks and valleys of weekly dosing

Some practitioners prefer it because of this, arguing that patients with certain metabolic variants may convert cyanocobalamin less efficiently