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Because GLP-1 medicines can also reduce insulin resistance, I had to reduce my long-acting insulin by about 20% to avoid hypoglycemia, which can be severe unless insulin therapy is modified before starting

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Prajapat VM, Mahajan S, Paul PG, et al

Another study identified isolated species, including Enterococcus faecalis , Clostridium perfringens , Clostridium bifermentans , and Clostridium butyricum , which exhibited GLP-1 inhibitory activity in the human cell line NCI-H716 74