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However, in specifically designed placebo-controlled studies of GLP-1 RAs among patients with HFrEF, there were no improvements in HRQoL

GLP-1 Receptor Agonists: The Reinforcements The FLOW trial, also published in the New England Journal of Medicine, tested semaglutide (Ozempic) in 3,533 patients with type 2 diabetes and CKD (Perkovic et al., 2024)

The absence of a preexisting T2DM diagnosis, the absence of any previous antidiabetic drug, and prescribing outside of the benefit acted as surrogate markers for potential off-label prescribing of the GLP-1 RA brand with the indication of T2DM

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Association between the serum folate levels and tea consumption during pregnancy