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Key Takeaways Mounjaro (tirzepatide) is injected subcutaneously into one of three approved areas: the abdomen, thigh, or back of the upper arm

Harpagoside, one of its active constituents, exerts neuroprotective effects by modulating endoplasmic reticulummitochondria coupling (MAMs), suppressing IP3R1/GRP75/VDAC1 complex expression, and maintaining neuronal calcium homeostasis

spread calories across 45 small meals rather than 23 large ones

Group V rats were induced with STZ intraperitonially (50 mg/kg b.w.t.) (diabetic control rats)