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Rose et al

Furthermore, to prevent irritation and maintain microbial defense, the pH of the nasal formulation should be adjusted slightly acidic, as lysozymes in nasal secretions effectively destroy bacteria at acidic pH but become inactivated under alkaline conditions, leaving tissue vulnerable to infection [101]

Al-Hadrawi DS, Al-Rubaye HT, Almulla AF, Al-Hakeim HK, Maes MF

Arch Pharm Res 46(4):207272

Laboratory research utilizes these structural insights to develop peptides with improved cellular uptake, enhanced selectivity, and reduced off-target effects, providing researchers with increasingly sophisticated tools for senescence research applications