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GLP-1 drugs have intrinsic potent anti-inflammatory action beyond their metabolic beneficial impact on glucose regulation and weight loss From an evolutionary perspective, either the inflammation is playing a beneficial role, at least for some of us, or it is the result of a relatively recent, extrinsic insult - pollution, microplastics, poor diet/changes in the microbiome, sedentary lifestyles, heat, and so on

Exerkine FNDC5/irisin-enriched exosomes promote proliferation and inhibit ferroptosis of osteoblasts through interaction with Caveolin-1

When one size does not fit all: reconsidering PCOS etiology, diagnosis, clinical subgroups, and subgroup-specific treatments

And the increases could be even higher, he said

Weyer C, Bogardus C, Pratley RE