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2022 Cochrane Review: Six RCTs in 1,089 men with subfertility taking 1,0003,000 mg/day carnitine for 8 weeks to 6 months found increased sperm motility and concentration at some timepoints but NO effect on live birth or pregnancy rates [3][47]

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age, gender, diet, gut microbiome, disease subtype, concurrent medications) that determine the metabolic state of a patient and affect the overall drug response [83,84]

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