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Compound versions of drugs are made for individual patients using raw ingredients

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Clinicopathologic correlation is required to establish a diagnosis of Peutz-Jeghers syndrome.Sebaceous lesions including sebaceous adenomas and sebaceomas, which are more commonly encountered as cutaneous tumors associated with Muir-Torre syndrome, have been described in patients with Peutz-Jeghers syndrome [44]

The available animal studies were not sufficient to resolve this concern because they did not provide a comprehensive dose-ranging, long-term carcinogenicity programme