In the study conducted by Nachvak et al., L-carnitine supplementation significantly increased serum total antioxidant capacity (TAC) and significantly reduced levels of myeloperoxidase (MPO), nitrotyrosine (NT), and high-sensitivity C-reactive protein (hs-CRP) compared to the placebo group
Note that hGPX4-C is a mutant form of hGPX4 with the active site selenocysteine mutated to cysteine (U46C), resulting in much lowered enzyme activity
The most common side effects are mild and digestive, such as nausea, bloating, or an upset stomach
Once reconstituted with bacteriostatic water, the liquid solution must be kept refrigerated at all times
UA supplementation may yield more pronounced effects in novice individuals, who possess greater capacity for both neural and structural adaptations