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The thiobarbituric acid reaction method was used to determine MDA content

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The split between weightloss and diabetes indications meant carriers and sponsors will need clear criteria on whether to restrict coverage to diabetes (and, if so, under what clinical rules), or to extend support to obesity and cardiometabolic risk reduction more broadly

Incorporation of glucose, pH, redox or externally responsive release motifs confines drug action to diseased microenvironments, while multifunctional theranostic designs couple imaging probes with therapeutic cargo to enable real-time visualization of biodistribution and receptor engagement