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These include: Nausea and vomiting often mild to moderate and typically diminishing over time Diarrhoea or constipation changes in bowel habits are common Abdominal pain or discomfort usually transient Reduced appetite which may contribute to weight loss Injection site reactions such as redness, itching or swelling at the injection site These symptoms are generally manageable and tend to improve after the first few weeks

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In the long run, the sustained improvement of liver function markers is closely related to a reduced risk of disease progression, including cirrhosis and HCC [45]

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Leveraging new technologies can provide deeper insights into how obesity-related metabolic changes influence disease progression and cancer development