endogenous glp 1 production GLP1-GIP receptor co-agonists: a promising evolution in the treatment of type 2 diabetes | Acta Diabetologica Frontiers | Mechanisms of action

At the root of the question on the future of compounded GLP-1RAs is whether widespread shortages will occur again

12 The timeline to approval is compressed into 2 to 3 years, compared to the decade-long slog required for an NME

This distinction matters clinically: preserved muscle maintains resting metabolic rate, improves body composition aesthetics, and supports long-term weight stability by preventing the metabolic adaptation that often follows muscle loss

Sustainability and nutritional balance are often more important than rapid short-term results

I also think its equally important to have realistic expectations of what these procedures can achieve