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However, inhibition of endonuclease activity of APE1, rather than REDOX function, could interact with NPM1 to trigger p53-mediated effects on colon cancer cell metabolism and improve its sensitivity to targeted drugs [22]

Effects of cadmium on ultrastructure and antioxidative defense system in hyperaccumulator and non-hyperaccumulator ecotypes of Sedum alfredii Hance

The therapeutic strategies targeting peroxynitrite involve three approaches: inhibiting its formation by reducing the concentrations of NO and O 2 or increasing superoxide dismutation by SOD

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While not a recognized diagnosis, it provides valuable insights into shared disease processes and therapeutic strategies