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The FDA-approved indications for cervical TDR are for single-level disease without significant facet disease and are primarily indicated for disc herniation with nerve root compression

Dresen E, Lee ZY, Hill A, Notz Q, Patel JJ, Stoppe C

Conclusions To overcome long-standing challenges associated with off-target radiation damage resulting in life-long dry mouth and poor quality of life, we sought to leverage our salivary gland tissue chip technology to identify candidate radioprotective drugs 19

This approach prevents lipodystrophy (fatty tissue changes) and allows inflammation to resolve before reusing the same location

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