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Based on these initial studies and comprehensive characterization, liraglutide was selected as having the best properties, combining high receptor potency with pharmacokinetics (PK) that are optimum for OD dosing ( Following the selection of liraglutide as the first GLP-1-based analog suitable for OD dosing, further analysis of its structural activity was published ( The Discovery of Semaglutide Successful clinical trials with exenatide and liraglutide led to an increased interest in GLP-1-based therapies

Throughout the trial, the team of researchers analyzed changes in the IGA 7-point score and clinical and instrumental erythema severity score (ESS)

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