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Thats consistent with nationwide trends

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For most people, the most noticeable urinary changes occur during weeks one through three and improve significantly by weeks four through six

Dehydration and Acute Kidney Injury: Severe gastrointestinal side effects from semaglutide can lead to dehydration and potentially acute kidney injury

However, these anecdotal reports cannot establish causation and may reflect reporting bias, as patients experiencing problems are more likely to seek information and share experiences than those without issues