(PubMed) Nijhoff WA, Mulder TP, Verhagen H, van Poppel G, Peters WH
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fewer side effects, better results
We found that PA-S14 promotes mitochondrial biogenesis via LKB1-AMPK-PGC-1 signaling pathway, which protects against renal TECs cell senescence, renal fibrosis in various CKD models, such as unilateral ureteral obstruction (UUO), unilateral ischemia-reperfusion injury (UIRI), adriamycin nephropathy and 5/6 nephrectomized model (Liu et al., 2022a) (Table 1)
We now have a couple of lines of evidence that are pretty compelling if you take all of these things together. Are GLP-1 Medications Approved to Prevent Cancer