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The ratio of Dihexa to inulin in the blood was used to correct for any blood contamination in brain regions, while higher ratios in brain regions compared to blood indicated active concentration

The body has a natural system to remove these reactive O2 species

Detox pathways are supported, but energy production may still feel suboptimal

These cells can be primed and activated after ICB treatment, enabling them to migrate to the tumor site and exert their effector function on cancer cells

Similarly, ROS-induced ER stress triggers the unfolded protein response (UPR), which leads to further cell apoptosis and the immune system targeting melanocytes 56