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And how might that differ from what we can activate peripherally with these medicines to produce powerful weight loss? Perhaps, he suggested, GLP-1R agonists that get into the brain more efficiently might produce more neuroprotection, but would they also lead to more adverse events
Patients with malnutrition, low body mass index, or unintended weight loss should discuss whether GLP-1-associated weight reduction could be detrimental to their overall health status
Even more striking, nearly half (45%) of the combination treatment group achieved 20% or greater total weight loss , compared to only 18% of the tirzepatide-only group
EMA approval typically trails the FDA by six to twelve months for comparable cardiometabolic compounds
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