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Medications : Drugs like metformin or proton pump inhibitors can interfere with B12 absorption

This includes people with pernicious anemia, a condition where the body lacks intrinsic factors, making it impossible to absorb B12 from food

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The derivation from native hGH provides biological plausibility: the C-terminal region of growth hormone has been known since the 1990s to possess independent lipolytic activity separate from the growth-promoting effects mediated by intact GH and IGF-1 signaling