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The dosage is often gradually increased over a few months to minimize side effects and improve effectiveness

The adverse effects of ICI therapy on the endocrine system vary significantly, from commonly occurring thyroid and pituitary disorders to relatively rare adrenal insufficiency and type 1 diabetes

However, higher doses may result in unwanted effects such as abnormal tissue growth and organ stress in test models

Your provider may recommend switching from Contrave to Wegovy (or vice versa) depending on how you respond to treatment

A dose of 0.25 mg of semaglutide, for example, isnt meant to produce significant results on its own