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The degradation kinetics of curcumin in the curcuminoid mixture showed a first-order response

As metformin continues to be a widely prescribed medication for conditions such as T2DM, PCOS, and metabolic syndrome, further research is warranted to explore its tissue-specific actions and refine the dosing strategies

At the same time, it is important to acknowledge the limitations of pivotal trials such as STEP and SELECT, whose generalisability is constrained by relatively short follow-up, notable dropout rates, and the predominance of Western cohorts

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Peptides like BPC-157 and TB-500 are not FDA-approved drugs