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Phase 2 trial establishing 24.2% mean weight loss at 12mg over 48 weeks, with dose-response data across the 1mg to 12mg range

Standard / Gradual Approach The Symlin label steps the dose up only after nausea resolves at least three days between increases starting at 15 mcg per meal in type 1 diabetes and titrating in 15 mcg increments toward 3060 mcg, or starting at 60 mcg and moving to 120 mcg in type 2 diabetes [1]

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