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After removing 398 duplicate articles, 691 articles were excluded based on screening of the titles and abstracts

10.1016/j.ijbiomac.2023.128023 43 HanN.PanZ.LiuG.YangR.YujingB

In humans and rodents, metformin is concentrated in the liver and blocking the uptake of metformin into the liver in mice prevents the ability of metformin to lower blood glucose levels (48,49)

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