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Hormonal imbalances associated with PCOS make it difficult to lose weight, yet some clinics wont perform egg retrievals on patients unless theyre below a certain BMI

Paradigm shift from GTR concept to biologics application decreased the complication rate and improved the patient reported outcome measures [78, 79]

Cell Metab 24:1530

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Tendon injuries initially suffer from: Poor blood supply Limited vascularity Slow nutrient delivery In rodent models, BPC-157 appears to: Upregulate VEGFR2 signalling Increase capillary density Improve microvascular perfusion Mechanistically: BPC-157 VEGFR2 activation PI3K/Akt pathway eNOS phosphorylation Increased nitric oxide Improved angiogenesis More vascularity = better nutrient and oxygen delivery to fibroblasts